反应详情

A suspension of 10 g. of dimethyl 6-chloro-2,4-pyrimidinedicarbamate-3-oxide in 40 ml. of methylene chloride is treated with 20 ml. of 1,2,5,6-tetrahydropyridine and stirred at room temperature under an argon atmosphere for 16 hours. The precipitate formed is filtered off and recrystallized from a mixture of methylene chloride and methanol, there being obtained pure dimethyl 6-[3,6-dihydro-1(2H)-pyridyl]-2,4-pyrimidinedicarbamate-3-oxide having a melting point of 203° C.

1. additionA suspension of 10 g
2. customThe precipitate formed
3. filtrationis filtered off
4. customrecrystallized from a mixture of methylene chloride and methanol, there