HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Phthalimide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Tryptamine | HCID 1150 | — |
| Reactant | Phthalic Anhydride | HCID 6811 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Phthalimide | HCID 6809 | — |
Reaction Steps
A solution of 3.20 g (20.0 m mol) of tryptamine and 3.10 g (20.0 m mol) of phthalic anhydride in 40 ml of toluene was refluxed under a Dean-Stark water separator for 12 h. Cooling, filtration and concentration of the filtrate gave a crude phthalimide which was recrystallized from ethanol to produce 4.85 g (84%), of phthalimide, mp 164°-165° C.; reported 164°-165° C.3
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04220774 |
| Source dataset | uspto-grants-1980_09 |
| ORD ID | ord-beb9b7be15ea42c4b1a6c19e8885cdad |
| Source note | uspto-grants-1980_09 |