HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4-Isopropylphenyl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-amine → N-[3-(4-Isopropylphenyl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl]-3-(4-methoxyphenyl)propionamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4-Isopropylphenyl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-amine | HCID 10519978 | — |
| Reactant | 3-(4-Methoxyphenyl)propionyl chloride | HCID 10932441 | — |
| Solvent | Ethyl acetate hexane | HCID 21226206 | — |
| Product | N-[3-(4-Isopropylphenyl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl]-3-(4-methoxyphenyl)propionamide | HCID 21961330 | 72% |
Reaction Steps
By using 3-(4-isopropylphenyl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-amine and 3-(4-methoxyphenyl)propionyl chloride, the title compound was synthesized according to Example 1b. Yield: 72%. Melting point: 188-191° C. (Ethyl acetate-hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07456162B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-807c5eb4413449269ff39e62ac6fa4a1 |
| Source note | uspto-grants-2008_11 |