HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfate → HCID 12018943, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfate | HCID 6497 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | METHYL 3-HYDROXYTHIENO[2,3-B]PYRIDINE-2-CARBOXYLATE | HCID 2727696 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 12018943 | HCID 12018943 | — |
Reaction Steps
995 mg of 3-hydroxy-2-methoxycarbonylthieno[2,3-b]pyridine (4.76 mmol, 1 eg.) is reflux heated for 4 hrs with 0.54 ml of dimethyl sulfate (5.71 mmol, 1.2 eq.) in 30 ml of acetone in the presence of 987 mg of potassium carbonate (7.14 mmol, 1.5 eq.). The insoluble is filtered, washed with acetone and vacuum evaporated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07456192B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-d0c6849a0d32487ea7448adda2865a8f |
| Source note | uspto-grants-2008_11 |