HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pentane → 4-(Bromomethyl)-2,6-dimethoxypyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pentane | HCID 8003 | — |
| Reactant | Phosphorus tribromide | HCID 24614 | — |
| Reactant | HCID 598131 | HCID 598131 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-(Bromomethyl)-2,6-dimethoxypyridine | HCID 17964963 | — |
Reaction Steps
1 g of (2,6-dimethoxypyridin-4-yl)methanol, prepared according to J. Heterocl. Chem., 1974, 11, 251, is dissolved in 20 ml of CH2Cl2, 0.84 ml of PBr3 is added and then the mixture is left stirring at for 10 hours. Pentane is added and the precipitate formed is filtered off, washed with pentane and then dried to produce 850 mg of the expected compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07456193B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-abf811d85d0042b2ac8fbfa98a089e11 |
| Source note | uspto-grants-2008_11 |