HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-3-chloropropane → HCID 23091623, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-3-chloropropane | HCID 8006 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4-(2-Methoxyethyl)piperidine--hydrogen chloride (1/1) | HCID 23091644 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 23091623 | HCID 23091623 | 88% |
Reaction Steps
4-(2-Methoxy-ethyl)-piperidine hydrochloride (1.5 g, 8.4 mmol), acetone (30 ml, 20 vol), 5M NaOH solution (6.03 ml, 3.6 eq.) and 1-bromo-3-chloropropane (3.96 g, 25.1 mmol, 3 eq.) were reacted together according to general procedure A to give the title compound (1.6 g, 88%) as a pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07456164B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-7594057554fa4a54ac0accb24f9500c2 |
| Source note | uspto-grants-2008_11 |