HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-3-chloropropane → 3-Chloropropyl(diethyl)amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-3-chloropropane | HCID 8006 | — |
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 3-Chloropropyl(diethyl)amine | HCID 66918 | 59.2% |
Reaction Steps
Diethyl-amine (7.27 ml, 70 mmol), acetone (15 ml, 3 vol), 5M NaOH solution (16.8 ml, 1.2 eq.) and 1-bromo-3-chloropropane (16.5 g, 105 mmol, 1.5 eq.) were reacted together according to general procedure A to give the title compound (6.2 g, 59%) as a colourless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07456164B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-c2c1bbbf84384ab69ed1cc1e433b4b2a |
| Source note | uspto-grants-2008_11 |