HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium methanethiolate → 4-[4-(morpholin-4-ylmethyl)tetrahydro-2H-pyran-4-yl]phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium methanethiolate | HCID 4378561 | — |
| Reactant | 4-{[4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl]methyl}-morpholine | HCID 68575527 | — |
| Product | 4-[4-(morpholin-4-ylmethyl)tetrahydro-2H-pyran-4-yl]phenol | HCID 68577166 | 75% |
Reaction Steps
The title compound (1.70 g, 75%) was prepared using 4-{[4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl]methyl}-morpholine and sodium thiomethoxide similarly to the procedure used for intermediate 72. HRMS ESI+ m/z 278.1740 [MH]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07456164B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-8d60cee9cf3c4124ad075c7a0c43ad50 |
| Source note | uspto-grants-2008_11 |