HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86592434, compound → HCID 9944929, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86592434 | HCID 86592434 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 9944929 | HCID 9944929 | 70% |
Reaction Steps
(+/−)-(3RS,4SR)-N-Benzyloxy-N-[4-butyl-1-(4-hydroxybenzyl)-2-oxopyrrolidin-3-ylmethyl]formamide (0.13 g, 0.32 mmol) was dissolved in methanol (5 mL) and stirred under a hydrogen balloon in the presence of palladium on activated carbon (30 mg) for 4 h. The reaction mixture was filtered, concentrated and the residue was purified by HPLC to afford the title compound as a white solid (0.071 g, 70%). MS(ES) m/e 321 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07456211B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-d6b310c6f51040c487444e5be85b4cf6 |
| Source note | uspto-grants-2008_11 |