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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 273191Generated: October 29, 2026

HCID 86592434, compound → HCID 9944929, compound

https://huagongshe.com/reaction/273191

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86592434HCID 86592434—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 9944929HCID 994492970%

Reaction Steps

(+/−)-(3RS,4SR)-N-Benzyloxy-N-[4-butyl-1-(4-hydroxybenzyl)-2-oxopyrrolidin-3-ylmethyl]formamide (0.13 g, 0.32 mmol) was dissolved in methanol (5 mL) and stirred under a hydrogen balloon in the presence of palladium on activated carbon (30 mg) for 4 h. The reaction mixture was filtered, concentrated and the residue was purified by HPLC to afford the title compound as a white solid (0.071 g, 70%). MS(ES) m/e 321 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07456211B2
Source datasetuspto-grants-2008_11
ORD IDord-d6b310c6f51040c487444e5be85b4cf6
Source noteuspto-grants-2008_11