Hydrochloric Acid → HCID 9958164, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of the product obtained in Example 19 (210 mg) in THF (5 ml) were added 0.5N LiOH (1.54 ml) and 3% H2O2 (65 μl) at 5° C. The mixture was stirred at 5° C. for 14 hours and acidified with 1 N HCl. The mixture was concentrated, diluted with H2O and the resulting precipitate was collected by filtration and washed with H2O to yield the title compound (171 mg). mp. 182-184° C.; IR (Nujol) 3295, 1729, 1711, 1653 cm−1; MS (ESI) m/z 514 (M−H)

Provenance & Evidence