HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → ethyl 2-ethoxy-3-(4-{2-[2-(pentafluoroethyl)-1H-benzimidazol-1 yl]ethoxy}phenyl)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Ethyl 2-ethoxy-3-[4-(2-bromoethoxy)-phenyl]propanoate | HCID 11002461 | — |
| Reactant | 2-(Pentafluoroethyl)-1H-benzimidazole | HCID 12751213 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | ethyl 2-ethoxy-3-(4-{2-[2-(pentafluoroethyl)-1H-benzimidazol-1 yl]ethoxy}phenyl)propanoate | HCID 86609608 | — |
Reaction Steps
This compound was prepared from ethyl 3-[4-(2-bromoethoxy)phenyl]-2-ethoxypropanoate (371 mg, 1 mmol), 2-(pentafluoroethyl)-1H-benzimidazole (259 mg, 1.1 mmol), K2CO3 (552 mg, 4 mmol) and DMF (5 ml) using the procedure described in Step B of Example 1. Yield 420 mg (84%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07456293B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-1c6e0ee8bd0e48ada264ea62952fff83 |
| Source note | uspto-grants-2008_11 |