2-Mercaptoethanol → HCID 66732788, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 50.4 g of 1-[4-(2-hydroxyethyl)phenylamino]-3-chloro-4-aminoanthraquinone Ic from Example 3 and 100 ml of dimethylformamide (DMF) is heated to 80° C. in a laboratory reaction apparatus. A further 50 ml of DMF and 11 g of 2-mercaptoethanol are then added. At an internal temperature of 83° C., 18.6 g of 30% aqueous sodium hydroxide solution are then slowly added dropwise and the mixture is stirred for 3 hours at 80° C. After cooling to RT, the precipitate is filtered off, washed with ethanol and dried in a vacuum drying chamber.

Provenance & Evidence