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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 273585Generated: October 30, 2026

Benzyl Bromide → HCID 168301709, compound

https://huagongshe.com/reaction/273585

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl BromideHCID 7498—
Reactantt-Butyl 4-(4-(5-(4-chlorophenyl)furan-2-carboxamido)phenyl)piperazine-1-carboxylateHCID 168301698—
ReagentSulfuric AcidHCID 1118—
Reagenttert-Butylimino-tri(pyrrolidino)phosphoraneHCID 3856267—
SolventDimethylformamideHCID 6228—
SolventDiglymeHCID 8150—
Productt-Butyl 4-(4-(5-(4-chlorophenyl)furan-2-carboxamido)phenyl)piperazine-1-carboxylateHCID 168301698—
ProductHCID 168301709HCID 16830170982%

Reaction Conditions

Temperature23 °C

Provenance & Evidence

DOI10.1038/s44160-023-00351-1
Source datasetCernak miniaturized N-alkylation with BOC deprotection
ORD IDord-590ef6cd4bfe433988e529ad0aacf0ee
Source noteCernak miniaturized N-alkylation with BOC deprotection