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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 273591Generated: October 30, 2026

2-Butene, 1-bromo-3-methyl- → HCID 168301708, compound

https://huagongshe.com/reaction/273591

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Butene, 1-bromo-3-methyl-HCID 70092—
Reactantt-Butyl 4-(4-(5-(4-chlorophenyl)furan-2-carboxamido)phenyl)piperazine-1-carboxylateHCID 168301698—
ReagentSulfuric AcidHCID 1118—
ReagentHCID 178418261HCID 178418261—
SolventDimethylformamideHCID 6228—
SolventDiglymeHCID 8150—
Productt-Butyl 4-(4-(5-(4-chlorophenyl)furan-2-carboxamido)phenyl)piperazine-1-carboxylateHCID 168301698—
ProductHCID 168301708HCID 16830170849%

Reaction Conditions

Temperature23 °C

Provenance & Evidence

DOI10.1038/s44160-023-00351-1
Source datasetCernak miniaturized N-alkylation with BOC deprotection
ORD IDord-8641c6c15e2b4806a609874bad9c2594
Source noteCernak miniaturized N-alkylation with BOC deprotection