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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 273605Generated: October 30, 2026

Butyl iodide → HCID 168301713, compound

https://huagongshe.com/reaction/273605

Reaction equation

Participants

RoleNameHCIDCharge
ReactantButyl iodideHCID 10962—
ReactantTert-butyl 4-(4-(5-(4-cyanophenyl)furan-2-carboxamido)phenyl)piperazine-1-carboxylateHCID 168301699—
ReagentSulfuric AcidHCID 1118—
Reagenttert-Butylimino-tri(pyrrolidino)phosphoraneHCID 3856267—
SolventDimethylformamideHCID 6228—
SolventDiglymeHCID 8150—
ProductTert-butyl 4-(4-(5-(4-cyanophenyl)furan-2-carboxamido)phenyl)piperazine-1-carboxylateHCID 168301699—
ProductHCID 168301713HCID 16830171373%

Reaction Conditions

Temperature23 °C

Provenance & Evidence

DOI10.1038/s44160-023-00351-1
Source datasetCernak miniaturized N-alkylation with BOC deprotection
ORD IDord-2b1a17958bd64b3bbf85105acf48ff35
Source noteCernak miniaturized N-alkylation with BOC deprotection