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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 273611Generated: October 29, 2026

2-(Bromomethyl)-1-methyl-1H-imidazole → HCID 178480588, compound

https://huagongshe.com/reaction/273611

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Bromomethyl)-1-methyl-1H-imidazoleHCID 23043578—
ReactantTert-butyl 4-(4-(5-(4-cyanophenyl)furan-2-carboxamido)phenyl)piperazine-1-carboxylateHCID 168301699—
ReagentSulfuric AcidHCID 1118—
ReagentHCID 178418261HCID 178418261—
SolventDimethylformamideHCID 6228—
SolventDiglymeHCID 8150—
ProductTert-butyl 4-(4-(5-(4-cyanophenyl)furan-2-carboxamido)phenyl)piperazine-1-carboxylateHCID 168301699—
ProductHCID 178480588HCID 17848058814%

Reaction Conditions

Temperature23 °C

Provenance & Evidence

DOI10.1038/s44160-023-00351-1
Source datasetCernak miniaturized N-alkylation with BOC deprotection
ORD IDord-f82f619cd0cb4db99d356ea2c7ff5473
Source noteCernak miniaturized N-alkylation with BOC deprotection