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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 273618Generated: October 29, 2026

2-(Bromomethyl)pyridine → HCID 178509568, compound

https://huagongshe.com/reaction/273618

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Bromomethyl)pyridineHCID 564209—
ReactantTert-butyl 4-(4-(5-(4-cyanophenyl)furan-2-carboxamido)phenyl)piperazine-1-carboxylateHCID 168301699—
ReagentSulfuric AcidHCID 1118—
ReagentSodium t-butoxideHCID 23676156—
SolventDimethylformamideHCID 6228—
SolventDiglymeHCID 8150—
ProductTert-butyl 4-(4-(5-(4-cyanophenyl)furan-2-carboxamido)phenyl)piperazine-1-carboxylateHCID 168301699—
ProductHCID 178509568HCID 17850956893%

Reaction Conditions

Temperature23 °C

Provenance & Evidence

DOI10.1038/s44160-023-00351-1
Source datasetCernak miniaturized N-alkylation with BOC deprotection
ORD IDord-e1930653897b4b25962bb1b8e76ba437
Source noteCernak miniaturized N-alkylation with BOC deprotection