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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 273620Generated: October 29, 2026

2-(Bromomethyl)-6-methylpyridine → HCID 57401826, compound

https://huagongshe.com/reaction/273620

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Bromomethyl)-6-methylpyridineHCID 12543733—
ReactantTert-butyl 4-(4-(5-(4-cyanophenyl)furan-2-carboxamido)phenyl)piperazine-1-carboxylateHCID 168301699—
ReagentSulfuric AcidHCID 1118—
Reagent2,N'3,N'3,N3,N3,N'5,N'5,N5,N5-nonamethyl-2,4,6-triaza-3lambda5,5lambda5-diphosphaocta-3,5-diene-3,3,5,5-tetramineHCID 3393106—
SolventDimethylformamideHCID 6228—
SolventDiglymeHCID 8150—
ProductHCID 57401826HCID 5740182629%
ProductTert-butyl 4-(4-(5-(4-cyanophenyl)furan-2-carboxamido)phenyl)piperazine-1-carboxylateHCID 168301699—

Reaction Conditions

Temperature23 °C

Provenance & Evidence

DOI10.1038/s44160-023-00351-1
Source datasetCernak miniaturized N-alkylation with BOC deprotection
ORD IDord-f6a8c9e7adb04de098163941d0c31959
Source noteCernak miniaturized N-alkylation with BOC deprotection