2,3-dihydro-1H-indol-7-yl(phenyl)methanone → (1H-Indol-7-yl)(phenyl)methanone

HRID 27363Notes

Reaction equation

HRID 27363 reaction equation
[C:1]([C:9]1[CH:10]=[CH:11][CH:12]=[C:13]2[C:17]=1[NH:16][CH2:15][CH2:14]2)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>[O-2].[O-2].[Mn+4]>[C:1]([C:9]1[CH:10]=[CH:11][CH:12]=[C:13]2[C:17]=1[NH:16][CH:15]=[CH:14]2)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 1

HCID 27418922,3-dihydro-1H-indol-7-yl(phenyl)methanone

Product 1

HCID 10878711(1H-Indol-7-yl)(phenyl)methanone

Reagents, catalysts & solvents 1

HCID 178418406HCID 178418406, compoundCatalyst

Procedure

dehydrogenating the 7-benzoylindoline produced in step (1) with 1 to 5 molar equivalents of manganese dioxide in the presence of an inert solvent at a reflux temperature to produce 7-benzoylindole;

Sources & evidence

ORD record
ord-def6d2af9e024ead8b2655362d911941
Source dataset
uspto-grants-1980_09
Patent number
US04221716

Reaction notes

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