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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 273636Generated: October 29, 2026

2-Butene, 1-bromo-3-methyl- → HCID 168301703, compound

https://huagongshe.com/reaction/273636

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Butene, 1-bromo-3-methyl-HCID 70092—
ReactantTert-butyl 4-(4-(5-(4-cyanophenyl)furan-2-carboxamido)phenyl)piperazine-1-carboxylateHCID 168301699—
ReagentSulfuric AcidHCID 1118—
Reagent2,N'3,N'3,N3,N3,N'5,N'5,N5,N5-nonamethyl-2,4,6-triaza-3lambda5,5lambda5-diphosphaocta-3,5-diene-3,3,5,5-tetramineHCID 3393106—
SolventDimethylformamideHCID 6228—
SolventDiglymeHCID 8150—
ProductTert-butyl 4-(4-(5-(4-cyanophenyl)furan-2-carboxamido)phenyl)piperazine-1-carboxylateHCID 168301699—
ProductHCID 168301703HCID 16830170345%

Reaction Conditions

Temperature23 °C

Provenance & Evidence

DOI10.1038/s44160-023-00351-1
Source datasetCernak miniaturized N-alkylation with BOC deprotection
ORD IDord-eb231ca2c2ae464d9e8ecb325ca04ec3
Source noteCernak miniaturized N-alkylation with BOC deprotection