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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 273642Generated: October 31, 2026

t-Butyl 4-(4-(5-(4-chlorophenyl)furan-2-carboxamido)phenyl)piperazine-1-carboxylate → t-Butyl 4-(4-(5-(4-chlorophenyl)furan-2-carboxamido)phenyl)piperazine-1-carboxylate

https://huagongshe.com/reaction/273642

Reaction equation

Participants

RoleNameHCIDCharge
Reactantt-Butyl 4-(4-(5-(4-chlorophenyl)furan-2-carboxamido)phenyl)piperazine-1-carboxylateHCID 168301698—
ReagentSulfuric AcidHCID 1118—
ReagentSodium t-butoxideHCID 23676156—
SolventDimethylformamideHCID 6228—
SolventDiglymeHCID 8150—
Productt-Butyl 4-(4-(5-(4-chlorophenyl)furan-2-carboxamido)phenyl)piperazine-1-carboxylateHCID 168301698—

Reaction Conditions

Temperature23 °C

Provenance & Evidence

DOI10.1038/s44160-023-00351-1
Source datasetCernak miniaturized N-alkylation with BOC deprotection
ORD IDord-7b084ea6053441bb99b1fe8e298e8ff3
Source noteCernak miniaturized N-alkylation with BOC deprotection