HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxy-3-hydroxymethyl-5-ethyl-6-methylpyridine → 2-Methoxy-5-ethyl-6-methylnicotinaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxy-3-hydroxymethyl-5-ethyl-6-methylpyridine | HCID 15228414 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 2-Methoxy-5-ethyl-6-methylnicotinaldehyde | HCID 10261679 | 90.1% |
Reaction Steps
Activated manganese dioxide (2.0 g) was added to a solution of 2-methoxy-3-hydroxymethyl-5-ethyl-6-methylpyridine (1.18 g, 6.5 mmol) in dry benzene (20 mL) and refluxed 5-10 hours. The warm suspension was filtered through a pad of anhydrous Na2SO4 and evaporated to yield 1.05 g (90%) of a viscous oil which solidified.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05387512 |
| Source dataset | uspto-grants-1995_02 |
| ORD ID | ord-d2bbc18a1e6b40b2ae6c5fe1e46175bf |
| Source note | uspto-grants-1995_02 |