HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diazomethane → Methyl 2-(2-bromoethyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diazomethane | HCID 9550 | — |
| Reactant | 2-(2-Bromoethyl)benzoic acid | HCID 18620818 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | Methyl 2-(2-bromoethyl)benzoate | HCID 12496479 | — |
Reaction Steps
2-(2-Bromoethyl)-benzoic acid (11.4 g, 50 mmol) is added to a solution of diazomethan in ether at 0° C. The reaction mixture is concentrated in vacuo, and the residue purified by chromatography to give the desired compound as a colourless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05387582 |
| Source dataset | uspto-grants-1995_02 |
| ORD ID | ord-da5ac1400293420aaaabc1b65bdad173 |
| Source note | uspto-grants-1995_02 |