HCID 22400080, compound → HCID 15389972, compound

HRID 273690Notes

Reaction equation

HRID 273690 reaction equation
[CH3:1][O:2][C:3]1[N:8]=[C:7]([O:9][CH3:10])[N:6]=[C:5]([O:11][CH:12]([C:23]([O:26][CH2:27][CH3:28])([CH3:25])[CH3:24])[C:13]([O:15]CC2C=CC=CC=2)=[O:14])[N:4]=1.[H][H]>C(O)C.[C].[Pd]>[CH3:10][O:9][C:7]1[N:8]=[C:3]([O:2][CH3:1])[N:4]=[C:5]([O:11][CH:12]([C:23]([O:26][CH2:27][CH3:28])([CH3:24])[CH3:25])[C:13]([OH:15])=[O:14])[N:6]=1

Participants

5

Reactant 2

HCID 22400080HCID 22400080, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 15389972HCID 15389972, compoundYield 95%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Conditions

Temperature
20 °C

Procedure

That is, in 200 ml of ethanol were dissolved 39.2 g (0.1 mol) of Compound 155 prepared in the above, (6), and 0.5 g of palladium carbon was added thereto as a catalyst. The mixture was stirred at room temperature (20° C.) for 1 hour while blowing hydrogen therein. Subsequently, the catalyst was removed by filtration, and the mother liquor was concentrated to obtain 28.6 g (yield: 95%) of the title compound as a colorless oily product.

Workup

  1. additionwas added
  2. customSubsequently, the catalyst was removed by filtration
  3. concentrationthe mother liquor was concentrated

Sources & evidence

ORD record
ord-38f91622e3f542b1be471b4d5620d663
Source dataset
uspto-grants-1995_02
Patent number
US05387575

Reaction notes

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