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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 273698Generated: October 27, 2026

3-Cyanomethyl-1-benzylpyrrolidine hydrochloride → 2-(Pyrrolidin-3-yl)acetonitrile hydrochloride

https://huagongshe.com/reaction/273698

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Cyanomethyl-1-benzylpyrrolidine hydrochlorideHCID 20078154—
ReactantHCID 178418361HCID 178418361—
SolventEthanolHCID 702—
Product2-(Pyrrolidin-3-yl)acetonitrile hydrochlorideHCID 2007813995%

Reaction Steps

Catalytic debenzylation, in the presence of hydrogen and palladised carbon, of 3-cyanomethyl-1-benzylpyrrolidine hydrochloride, in ethanol, makes it possible to obtain the desired compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05387591
Source datasetuspto-grants-1995_02
ORD IDord-015b3688a3b54ed6b7e2ff711a2617c7
Source noteuspto-grants-1995_02