Benzene, 1-bromo-4-(trifluoromethyl)- → HCID 18998431, compound

Participants

Reaction Steps

This compound was prepared from 1,4-cyclohexanedione monoethylene ketal (10.9 g, 70 mmole) and the Grignard reagent prepared from 4-bromobenzotrifluoride (25.0 g, 110 mmole) and magnesium (2.7 g, 110 mmole) in a manner similar to example 3. The crude product was crystallized from petroleum ether to give the product (20 g, 94.8% ). Calc'd. for C15H17F3O3 : C, 59.60%; H, 5.67%. Found: C, 59.77%; H, 5.62%.

Provenance & Evidence