HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → 2,2-Dimethyl-4-oxo-3,4-dihydro-2H-1-benzopyran-6-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 3-Acetyl-4-hydroxybenzonitrile | HCID 12332832 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2,2-Dimethyl-4-oxo-3,4-dihydro-2H-1-benzopyran-6-carbonitrile | HCID 10954598 | — |
Reaction Steps
A mixture of 81 g of 3-acetyl-4-hydroxybenzonitrile, 48 ml of acetone, 11.8 ml of pyrrolidine and 300 ml of toluene is allowed to stand at 20° for 1 hour, then boiled for 2 hours in a water separator and cooled. After customary working up, 2,2-dimethyl-6-cyano-4-chromanone is obtained, m.p. 119°-120°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05387587 |
| Source dataset | uspto-grants-1995_02 |
| ORD ID | ord-bedab2e0fc4243f087935487d1a27e38 |
| Source note | uspto-grants-1995_02 |