Sodium Hydroxide → HCID 14798434, compound

HRID 273752Notes

Reaction equation

HRID 273752 reaction equation
[CH3:1][C:2]1([CH3:22])[CH:11](O)[CH:10]([S:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=2)[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:20]#[N:21])[CH:8]=2)[O:3]1.[OH-].[Na+]>O1CCOCC1>[CH3:1][C:2]1([CH3:22])[CH:11]=[C:10]([S:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=2)[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:20]#[N:21])[CH:8]=2)[O:3]1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 14798424HCID 14798424, compound

Product 1

HCID 14798434HCID 14798434, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

A mixture of 10 g of 2,2-dimethyl-4-(2-pyridylthio)-6-cyano-3-chromanol, 3 g of sodium hydroxide a 350 ml of dioxane is boiled for 20-minutes. The mixture is cooled and filtered, the filtrate is evaporated and 2,2-dimethyl-4-(2-pyridylthio)-6-cyano-3-chromene, m.p. 110°-112°, is obtained.

Workup

  1. waitis boiled for 20-minutes
  2. temperatureThe mixture is cooled
  3. filtrationfiltered
  4. customthe filtrate is evaporated

Sources & evidence

ORD record
ord-9fe1a5f6664348b5b7d1409d35070c06
Source dataset
uspto-grants-1995_02
Patent number
US05387587

Reaction notes

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