化工社化工社 化学情報印刷レポート · 研究参考用
Hydrogen Bromide → 2-Phenyl-2-cyclohexen-1-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrogen Bromide | HCID 260 | — |
| 反応物 | 2-Bromo-6-phenylcyclohexanone | HCID 12779129 | — |
| 溶媒 | Butyl ether | HCID 8909 | — |
| 生成物 | 2-Phenyl-2-cyclohexen-1-one | HCID 1201401 | 80% |
反応手順
A suspension of 4.97 g (19.6 mmole) of 2-bromo-6-phenylcyclohexanone in 120 mL of di-n-butyl ether was heated at 175° C. for 7 hours, at which point evolution of gaseous HBr had essentially ceased. The mixture was concentrated in vacuo and the residue purified by flash chromatography with 75:25 methylene chloride: hexanes to provide 2.69 g (80%) of a white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05387595 |
| 出典データセット | uspto-grants-1995_02 |
| ORD ID | ord-edfe22590e604754beb43689d11c139e |
| 出典メモ | uspto-grants-1995_02 |