反应详情

A mixture of 9.23 g. of 3-nitro-4-chloro-benzophenone, 10 ml. of ethanol and 10.3 g. of N-methyl-N-octylamine is stirred at 80° to 85° C. for 30 minutes, and then the mixture is poured onto 100 ml. of ice water. The aqueous phase is extracted with 2×75 ml. of benzene. The benzene phases are combined, washed with distilled water until chloride-free, dried over anhydrous magnesium sulphate, filtered, and evaporated in vacuo. 11.57 g. of 3-nitro-4-(N-methyl-N-octylamino)-benzophenone are obtained in the form of an oily residue. On the basis of thin layer chromatographical examination, a pure, uniform product is obtained.

1. additionA mixture of 9.23 g
2. additionthe mixture is poured onto 100 ml
3. extractionThe aqueous phase is extracted with 2×75 ml
4. washwashed with distilled water until chloride-free
5. dry with materialdried over anhydrous magnesium sulphate
6. filtrationfiltered
7. customevaporated in vacuo