HCID 20094336, compound → 1-[7-Amino-5-(2-bromopropyl)-2,3-dihydro-1H-indol-1-yl]ethan-1-one

Participants

Reaction Steps

To a solution of 1-acetyl-5-(2-bromopropyl)-7-nitroindoline (50 g) in ethanol (1.5 l) was added platinum oxide (2.5 g), and the mixture was stirred at room temperature for 4 hours under an atmosphere of hydrogen. After the catalyst was filtered off, the filtrate was evaporated under reduced pressure to give 45 g of 1-acetyl-7-amino-5-(2-bromopropyl)indoline.

Provenance & Evidence