1-Bromo-5-chloropentane → alpha-(5-Chloropentyl)-alpha-(cyclohexylthio)-3,4-dimethoxy-benzeneacetonitrile

HRID 274012Notes

Reaction equation

HRID 274012 reaction equation
[CH:1]1([S:7][CH:8]([C:11]2[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[C:13]([O:19][CH3:20])[CH:12]=2)[C:9]#[N:10])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.Br[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][Cl:27]>>[Cl:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][C:8]([S:7][CH:1]1[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1)([C:11]1[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[C:13]([O:19][CH3:20])[CH:12]=1)[C:9]#[N:10]

Participants

3

Reactant 2

HCID 960701-Bromo-5-chloropentaneHCID 10541608alpha-(Cyclohexylthio)-3,4-dimethoxybenzeneacetonitrile

Product 1

HCID 11795020alpha-(5-Chloropentyl)-alpha-(cyclohexylthio)-3,4-dimethoxy-benzeneacetonitrile

Procedure

The procedure of Example 2 is repeated using 3.0 g of α-(cyclohexylthio)-3,4-dimethoxy benzeneacetonitrile and 2.0 mL of bromo-5-chloropentane. This affords 3.1 g of the desired product as a colorless oil.

Sources & evidence

ORD record
ord-bad8afed74174460bbcc6d78f348d4fd
Source dataset
uspto-grants-1995_02
Patent number
US05387685

Reaction notes

Loading…