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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 274016Generated: October 31, 2026

Benzylamine → 2,3-Dihydro-5-methoxy-6-(phenylmethoxy)-2-(phenylmethyl)-1H-isoindole

https://huagongshe.com/reaction/274016

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzylamineHCID 7504—
ReactantBis(chloromethyl)-4-methoxy-5-(phenylmethoxy)benzeneHCID 10591097—
Product2,3-Dihydro-5-methoxy-6-(phenylmethoxy)-2-(phenylmethyl)-1H-isoindoleHCID 10736303—

Reaction Steps

The procedure of Example 26 is repeated using 1.0 g of bis(chloromethyl)-4-methoxy-5-(phenylmethoxy)benzene and 0.6 mL of benzyl amine. This affords 0.74 g of the desired product as a beige solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05387685
Source datasetuspto-grants-1995_02
ORD IDord-c20aaba0759e4bea935482527264e692
Source noteuspto-grants-1995_02