反应详情

A mixture of 1-(6-chloro-2-pyridyl)ethanol (2.13 g) and manganese dioxide (8.4 g) in chloroform (21 ml) was refluxed for 8 hours. After cooling, the mixture was filtered through celite pad and the filtrate was evaporated in vacuo. The residue was purified by distillation under reduced pressure to give 2-acetyl-6-chloropyridine (1.84 g).

1. temperaturewas refluxed for 8 hours
2. temperatureAfter cooling
3. filtrationthe mixture was filtered through celite pad
4. customthe filtrate was evaporated in vacuo
5. distillationThe residue was purified by distillation under reduced pressure