HCID 86748446, compound → HCID 20094824, compound

Participants

Reaction Steps

A solution of ethyl (E)-3-(8-oxo-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)acrylate (400 mg) in ethanol (8 ml) was hydrogenated over 10% palladium on carbon (24 mg). After removing the catalyst, the solution was evaporated in vacuo and the residue was purified by column chromatography on silica gel with a mixture of n-hexane and ethyl acetate (10:1) as an eluent to give ethyl 3-(8-oxo-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)propionate (311 mg).

Provenance & Evidence