Ammonia → HCID 18999537, compound

HRID 274116Notes

Reaction equation

HRID 274116 reaction equation
O[N:2]=[C:3]1[CH2:8][CH2:7][CH2:6][CH2:5][CH:4]1[CH2:9][C:10]1[CH:15]=[CH:14][C:13]([CH2:16][C:17]([O:19][CH2:20][CH3:21])=[O:18])=[CH:12][CH:11]=1.N>C(O)C>[NH2:2][CH:3]1[CH2:8][CH2:7][CH2:6][CH2:5][CH:4]1[CH2:9][C:10]1[CH:11]=[CH:12][C:13]([CH2:16][C:17]([O:19][CH2:20][CH3:21])=[O:18])=[CH:14][CH:15]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 73508032HCID 73508032, compound

Product 1

HCID 18999537HCID 18999537, compoundYield 39.1%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Obtained by operating as in example 1b from 15.5 g (56.7 mmoles) of ethyl 4-[(2-hydroxyiminocyclohexyl)methyl]benzeneacetate in ethanol saturated with NH3. After treatment, 6.1 g (yield=39.1%) of a yellow-green oil is isolated which is used without any other purification.

Workup

  1. customObtained

Sources & evidence

ORD record
ord-686e766670d34529885ee1440388f9d9
Source dataset
uspto-grants-1995_02
Patent number
US05387709

Reaction notes

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