HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylamine → HCID 18999574, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylamine | HCID 7912 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 80799-19-5 | HCID 12833029 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Solvent | 1,3-Dimethyl-2-imidazolidinone | HCID 6661 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | HCID 18999574 | HCID 18999574 | 44% |
Reaction Steps
Obtained by operating as in example 87a, from 19.7 g (195 mmoles) of diisopropylamine, 122 ml (195 mmoles) of a 1.6M solution of n-butyllithium in hexane, 45 ml of 1,3-dimethylimidazolidin-2-one, 21.8 g of 2,2,3,3-tetramethylcyclopropanecarbonitrile (prepared according to patent FR 2,479,192), 51.9 g (180.5 mmoles) of the compound prepared in example 26a in 295 ml tetrahydrofuran. After distillation, there is obtained 20 g (yield=44.0%) of a thick yellow oil. b.p.0.8 =185°-205° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05387709 |
| Source dataset | uspto-grants-1995_02 |
| ORD ID | ord-f00311c7e55e43e5bee4ceaff97473d0 |
| Source note | uspto-grants-1995_02 |