HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl N-(2-chloroacetyl)carbamate → 6-(Methylsulfonyl)imidazo[1,2-a]pyridine-2-carbamic acid, methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl N-(2-chloroacetyl)carbamate | HCID 518783 | — |
| Reactant | 5-Methanesulfonylpyridin-2-amine | HCID 17861008 | — |
| Solvent | Hexamethylphosphoramide | HCID 12679 | — |
| Product | 6-(Methylsulfonyl)imidazo[1,2-a]pyridine-2-carbamic acid, methyl ester | HCID 131711877 | — |
Reaction Steps
A suspension of 2-amino-5-(methylsulfonyl)pyridine (58.7 mmol) and methyl(chloroacetyl)carbamate (70 mmol) in 88 ml of HMPT is treated in a manner similar to that described above with respect to Example 1D to yield the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04221796 |
| Source dataset | uspto-grants-1980_09 |
| ORD ID | ord-db005d4623b34cfda72b285714466d5e |
| Source note | uspto-grants-1980_09 |