HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloroethyl isocyanate → 2-(2-Oxazolin-2-ylamino)-isoindoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloroethyl isocyanate | HCID 16035 | — |
| Reactant | 1,3-Dihydro-2H-isoindol-2-amine | HCID 12735618 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2-(2-Oxazolin-2-ylamino)-isoindoline | HCID 23342934 | — |
Reaction Steps
3.2 ml of (0.027 M) chlorethyl isocyanate in 15 ml of toluene are added dropwise to 5 g of (0.027 M) 2-amino-isoindoline in 100 ml toluene at a temperature of 20° to 30° C. After 1 hour, the precipitate is sucked off, washed with toluene and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04221798 |
| Source dataset | uspto-grants-1980_09 |
| ORD ID | ord-6e35732ca4e04b0291a26a336ee10396 |
| Source note | uspto-grants-1980_09 |