HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoro-6-phenylsulfonylpyridine → 2-Propyn-1-yl-6-fluoropyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoro-6-phenylsulfonylpyridine | HCID 20092124 | — |
| Reactant | HCID 178419101 | HCID 178419101 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-Propyn-1-yl-6-fluoropyridine | HCID 45079252 | — |
Reaction Steps
A mixture of 0.06 mol of propynylmagnesiumbromide and 25 ml of THF is added at 40°-40° C. [sic] to a mixture of 0.05 mol of 2A and 15 ml of THF. The mixture is stirred at room temperature for 2 hours and subjected to customary work-up. The unpurified product is processed further as in 10B.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05389291 |
| Source dataset | uspto-grants-1995_02 |
| ORD ID | ord-682faa98b7a5493d912afe71273901d5 |
| Source note | uspto-grants-1995_02 |