Benzyl bromoacetate → HCID 53926892, compound

Participants

Reaction Steps

6.4 g (0.03 mol) of (5-(4-cyanobenzylidene)-2,4-dioxoimidazolidine and 3.5 g (0.031 mol) of potassium tert-butylate are dissolved in 30 ml of dimethylformamide. After addition of 7.1 g (0.031 mol) of benzyl bromoacetate, the mixture is stirred at room temperature for 7 hours, heated briefly to 100° C. and concentrated. Water is added to the residue, and the mixture is extracted with ethyl acetate. The product crystallises out of the ethyl acetate phase, or can be precipitated by addition of heptane.

Provenance & Evidence