HCID 845978, compound → HCID 67784017, compound

HRID 274262Notes

Reaction equation

[OH:1][CH2:2][C:3]1[CH2:4][S:5][C@@H:6]2[CH:26]([NH:27][C:28](=[O:37])[CH2:29][O:30][C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)[C:25](=[O:38])[N:7]2[C:8]=1[C:9]([O:11][CH:12]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[O:10].[C:39]1([CH:45]([C:56]2[CH:61]=[CH:60][CH:59]=[CH:58][CH:57]=2)[O:46][C:47]([C:49]2[CH:54]=[CH:53][C:52](O)=[CH:51][CH:50]=2)=[O:48])[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=1>>[C:39]1([CH:45]([C:56]2[CH:61]=[CH:60][CH:59]=[CH:58][CH:57]=2)[O:46][C:47]([C:49]2[CH:50]=[CH:51][C:52]([O:1][CH2:2][C:3]3[CH2:4][S:5][C@@H:6]4[CH:26]([NH:27][C:28](=[O:37])[CH2:29][O:30][C:31]5[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=5)[C:25](=[O:38])[N:7]4[C:8]=3[C:9]([O:11][CH:12]([C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=3)[C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[O:10])=[CH:53][CH:54]=2)=[O:48])[CH:40]=[CH:41][CH:42]=[CH:43][CH:44]=1

Participants

Reactant 2

HCID 845978HCID 845978, compound

HCID 67783388HCID 67783388, compound

Product 1

HCID 67784017HCID 67784017, compound

Procedure

The procedure described in Example 1(a) was repeated, but using 2.00 g of diphenylmethyl 3-hydroxymethyl-7-phenoxyacetamido-3-cephem-4-carboxylate and p-(diphenylmethoxycarbonyl)phenol, to afford 864 mg of the title compound as a powder.

Sources & evidence

ORD record: ord-c1105113e9744ecea51921d6948f28e0
Source dataset: uspto-grants-1995_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05389626

Reaction notes

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