3-Cyanophenol → HCID 67783449, compound

HRID 274264Notes

Reaction equation

[O:1]([CH2:8][C:9]([NH:11][CH:12]1[C:37](=[O:38])[N:14]2[C:15]([C:21]([O:23][CH:24]([C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)[C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)=[O:22])=[C:16]([CH2:19][OH:20])[CH2:17][S:18][C@H:13]12)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:39]([C:41]1[CH:42]=[C:43](O)[CH:44]=[CH:45][CH:46]=1)#[N:40]>>[C:39]([C:41]1[CH:46]=[C:45]([CH:44]=[CH:43][CH:42]=1)[O:20][CH2:19][C:16]1[CH2:17][S:18][C@@H:13]2[CH:12]([NH:11][C:9](=[O:10])[CH2:8][O:1][C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)[C:37](=[O:38])[N:14]2[C:15]=1[C:21]([O:23][CH:24]([C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1)[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1)=[O:22])#[N:40]

Participants

Reactant 2

HCID 133943-Cyanophenol

HCID 67783388HCID 67783388, compound

Product 1

HCID 67783449HCID 67783449, compound

Procedure

The procedure described in Example 1(a), was repeated, but using 2.00 g of diphenylmethyl 7-phenoxyacetamido-3-hydroxymethyl-3-cephem-4-carboxylate and m-cyanophenol, to afford 490 mg of the title compound as a powder.

Sources & evidence

ORD record: ord-3baa754df6bb44da8fc1770bed14aca7
Source dataset: uspto-grants-1995_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05389626

Reaction notes

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