HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-chlorobenzyl)-4,5,6,7-tetrahydro-3H-azepine → 2-[(4-Chlorophenyl)methyl]azepane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-chlorobenzyl)-4,5,6,7-tetrahydro-3H-azepine | HCID 23342815 | — |
| Catalyst | Platinum | HCID 23939 | — |
| Product | 2-[(4-Chlorophenyl)methyl]azepane | HCID 3933809 | — |
Reaction Steps
Hydrogenate the thus-obtained 2-(4-chlorobenzyl)-4,5,6,7-tetrahydro-3H-azepine with platinum/active carbon/ hydrogen. Filter out the catalyst, concentrate the filtrate and distil to obtain 61.9 g (68% of theory) of the title compound with a BP of 93° at 0.1 mm of Hg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04221788 |
| Source dataset | uspto-grants-1980_09 |
| ORD ID | ord-a9a8a7247d0e458c9769f6464a652878 |
| Source note | uspto-grants-1980_09 |