6-Chloro-7-methyl-[1,2,4]triazolo[1,5-b]pyridazine → 1-Pentanesulfonamide, 3,3-dimethyl-5-((7-methyl(1,2,4)triazolo(1,5-b)pyridazin-6-yl)oxy)-

HRID 274275Notes

Reaction equation

HRID 274275 reaction equation
CN(C=[N:5][S:6]([CH2:9][CH2:10][C:11]([CH3:16])([CH3:15])[CH2:12][CH2:13][OH:14])(=[O:8])=[O:7])C.Cl[C:18]1[C:19]([CH3:27])=[CH:20][C:21]2[N:22]([N:24]=[CH:25][N:26]=2)[N:23]=1>>[CH3:16][C:11]([CH3:15])([CH2:10][CH2:9][S:6](=[O:7])(=[O:8])[NH2:5])[CH2:12][CH2:13][O:14][C:18]1[C:19]([CH3:27])=[CH:20][C:21]2[N:22]([N:24]=[CH:25][N:26]=2)[N:23]=1

Participants

3

Reactant 2

HCID 118051586-Chloro-7-methyl-[1,2,4]triazolo[1,5-b]pyridazineHCID 53804547HCID 53804547, compound

Product 1

HCID 30737931-Pentanesulfonamide, 3,3-dimethyl-5-((7-methyl(1,2,4)triazolo(1,5-b)pyridazin-6-yl)oxy)-

Procedure

Using 5-(N,N-dimethylaminomethylene)aminosulfonyl-3,3-dimethyl-1-pentanol and 6-chloro-7-methyl[1,2,4]triazolo[1,5-b]pyridazine, the same reaction as in Example 6 was conducted to produce the title compound. m.p. 143°-144° C.

Workup

  1. customthe same reaction as in Example 6

Sources & evidence

ORD record
ord-95a9268a8afe4d03a6901880eb2fc8d9
Source dataset
uspto-grants-1995_02
Patent number
US05389633

Reaction notes

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