6-Chloro-7-methyl-[1,2,4]triazolo[1,5-b]pyridazine → 3-Methyl-2-{[(7-methyl[1,2,4]triazolo[1,5-b]pyridazin-6-yl)oxy]methyl}butane-1-sulfonamide

HRID 274277Notes

Reaction equation

HRID 274277 reaction equation
CN(C=[N:5][S:6]([CH2:9][CH:10]([CH:13]([CH3:15])[CH3:14])[CH2:11][OH:12])(=[O:8])=[O:7])C.Cl[C:17]1[C:18]([CH3:26])=[CH:19][C:20]2[N:21]([N:23]=[CH:24][N:25]=2)[N:22]=1>>[CH:13]([CH:10]([CH2:9][S:6](=[O:7])(=[O:8])[NH2:5])[CH2:11][O:12][C:17]1[C:18]([CH3:26])=[CH:19][C:20]2[N:21]([N:23]=[CH:24][N:25]=2)[N:22]=1)([CH3:14])[CH3:15]

Participants

3

Reactant 2

HCID 118051586-Chloro-7-methyl-[1,2,4]triazolo[1,5-b]pyridazineHCID 53813453HCID 53813453, compound

Product 1

HCID 30737953-Methyl-2-{[(7-methyl[1,2,4]triazolo[1,5-b]pyridazin-6-yl)oxy]methyl}butane-1-sulfonamide

Procedure

Using 3-(N,N-dimethylaminomethylene)aminosulfonyl-2-isopropyl-1-propanol and 6-chloro-7-methyl[1,2,4]triazolo[1,5-b]pyridazine, the same reaction as in Example 6 was conducted to produce the title compound. m.p. 196°-197° C.

Workup

  1. customthe same reaction as in Example 6

Sources & evidence

ORD record
ord-f2f08a6109a7481297eb97a18b836d0e
Source dataset
uspto-grants-1995_02
Patent number
US05389633

Reaction notes

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