6-Chloro-2,7-dimethyl[1,2,4]triazolo[1,5-b]pyridazine → 1-Butanesulfonamide, 2-(((2,7-dimethyl(1,2,4)triazolo(1,5-b)pyridazin-6-yl)oxy)methyl)-2-methyl-

HRID 274280Notes

Reaction equation

HRID 274280 reaction equation
CN(C=[N:5][S:6]([CH2:9][C:10]([CH2:14][CH3:15])([CH3:13])[CH2:11][OH:12])(=[O:8])=[O:7])C.Cl[C:17]1[C:18]([CH3:27])=[CH:19][C:20]2[N:21]([N:23]=[C:24]([CH3:26])[N:25]=2)[N:22]=1>>[CH2:14]([C:10]([CH3:13])([CH2:9][S:6](=[O:7])(=[O:8])[NH2:5])[CH2:11][O:12][C:17]1[C:18]([CH3:27])=[CH:19][C:20]2[N:21]([N:23]=[C:24]([CH3:26])[N:25]=2)[N:22]=1)[CH3:15]

Participants

3

Reactant 2

HCID 107261326-Chloro-2,7-dimethyl[1,2,4]triazolo[1,5-b]pyridazineHCID 544433203-(N,N-dimethylaminomethylene)aminosulfonyl-2-ethyl-2-methyl-1-propanol

Product 1

HCID 30737991-Butanesulfonamide, 2-(((2,7-dimethyl(1,2,4)triazolo(1,5-b)pyridazin-6-yl)oxy)methyl)-2-methyl-

Procedure

Using 3-(N,N-dimethylaminomethylene)aminosulfonyl-2-ethyl-2-methyl-1-propanol and 6-chloro-2,7-dimethyl[1,2,4]triazolo[1,5-b]pyridazine, the same reaction as in Example 6 was conducted to produce the title compound. m.p. 194°-195° C.

Workup

  1. customthe same reaction as in Example 6

Sources & evidence

ORD record
ord-2110b5f2589f44628cbf239c8776778d
Source dataset
uspto-grants-1995_02
Patent number
US05389633

Reaction notes

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