HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiosemicarbazide → 5-(2-amino-6H-1,3,4-thiadiazin-5-yl)-3-nitropyrocatechol hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiosemicarbazide | HCID 2723789 | — |
| Reactant | 2-Bromo-1-(3,4-dihydroxy-5-nitro-phenyl)-ethanone | HCID 21845596 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | 5-(2-amino-6H-1,3,4-thiadiazin-5-yl)-3-nitropyrocatechol hydrobromide | HCID 135665327 | — |
Reaction Steps
A solution of 1.38 g of 2-bromo-3',4'-dihydroxy-5'-nitroacetophenone and 461 mg of thiosemicarbazide in 20 ml of n-butanol is heated to boiling under reflux for 60 minutes. After cooling to room temperature the crystals are filtered under suction and recrystallized from n-butanol. There is obtained 5-(2-amino-6H-1,3,4-thiadiazin-5-yl)-3-nitropyrocatechol hydrobromide of m.p. 265°-267°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05389653 |
| Source dataset | uspto-grants-1995_02 |
| ORD ID | ord-2e434c7299e3461bb2b24c3e639093e1 |
| Source note | uspto-grants-1995_02 |