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HRID274521

反应详情

EQUATION

反应方程式

HRID 274521 的结构方程式

REACTANTS

反应物

2
结构：CC(=O)[O-].[Na+]
HCID517045

Sodium Acetate

C2H3NaO2

结构：COc1cc(C(=O)Oc2ccccc2C(C)=O)cc([N+](=O)[O-])c1OC
HCID21458954

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc(-c2cc(=O)c3ccccc3o2)cc([N+](=O)[O-])c1OC
HCID21459108

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(=O)O
溶剂HCID176

Acetic Acid

C2H4O2

PROCEDURE

实验过程

A solution of 2.0 g of o-acetylphenyl 3,4-dimethoxy-5-nitrobenzoate in 12.5 ml of glacial acetic acid is treated with 0.94 g of sodium acetate and held at the reflux temperature for 4 hours. After cooling the mixture is poured into ice-water. The separated crystals are filtered under suction. After recrystallization from ethyl acetate/hexane there is obtained 2-(3,4-dimethoxy-5-nitrophenyl)-4H-1-benzopyran-4-one in the form of colorless crystals of m.p. 216°-217°.

WORKUP

后处理

  1. temperatureAfter cooling the mixture
  2. filtrationThe separated crystals are filtered under suction
  3. customAfter recrystallization from ethyl acetate/hexane there