Sodium Hydroxide → HCID 178441471, compound

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Reaction Steps

A solution of methyl 2-butyl-1-[[4-[2-(1H-tetrazol-5-yl)-1-pyrrolyl]phenyl]methyl]benzimidazole-7-carboxylate (0.85 g) in methanol (10 ml) containing 1N aqueous NaOH (5.7 ml) was heated under reflux for 2 hours. After evaporation of methanol, the residue was neutralized with 1N aqueous hydrochloric acid to precipitate crystals. Recrystallization from chloroform-methanol afforded colorless prisms (0.71 g, 78%), m.p. 165°-167° C.

Provenance & Evidence